Supragranular Pyramidal Cells Exhibit Early Metabolic Alterations in the 3xTg-AD Mouse Model of Alzheimer’s Disease

The impairment of cerebral glucose utilization is an early and predictive biomarker of Alzheimer’s disease (AD) that is likely to contribute to memory and cognition disorders during the progression of the pathology. Yet, the cellular and molecular mechanisms underlying these metabolic alterations re...

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Publicado en:Front Cell Neurosci
Autores principales: Piquet, Juliette, Toussay, Xavier, Hepp, Régine, Lerchundi, Rodrigo, Le Douce, Juliette, Faivre, Émilie, Guiot, Elvire, Bonvento, Gilles, Cauli, Bruno
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060432/
https://ncbi.nlm.nih.gov/pubmed/30072874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00216
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