3xTg-AD Mice Exhibit an Activated Central Stress Axis during Early-Stage Pathology

Activation of the hypothalamic-pituitary-adrenal (HPA) axis occurs in response to the organism’s innate need for homeostasis. The glucocorticoids (GCs) that are released into the circulation upon acute activation of the HPA axis perform stress-adaptive functions and provide negative feedback to turn...

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Autori principali: Hebda-Bauer, Elaine K., Simmons, Tracy A., Sugg, Andrew, Ural, Eren, Stewart, James A., Beals, James L., Wei, Qiang, Watson, Stanley J., Akil, Huda
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525735/
https://ncbi.nlm.nih.gov/pubmed/22976078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2012-121438
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