N-acetylcysteine suppresses colistimethate sodium-induced nephrotoxicity via activation of SOD2, eNOS, and MMP3 protein expressions

Objective: To investigate the molecular mechanisms of colistimethate sodium-induced nephrotoxicity and the protective effect of N-acetylcysteine (NAC) against nephrotoxicity. Methods: Twenty-eight Wistar rats were divided into four groups comprised of control, colistin, NAC, and colistin–NAC co-trea...

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Bibliografiske detaljer
Udgivet i:Ren Fail
Main Authors: Ceylan, Bahadir, Ozansoy, Mehmet, Kılıç, Ülkan, Yozgat, Yasemin, Ercan, Çilem, Yıldız, Pelin, Aslan, Turan
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Laboratory Study
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060374/
https://ncbi.nlm.nih.gov/pubmed/30035652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/0886022X.2018.1489286
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