N-Acetylcysteine prevents ifosfamide-induced nephrotoxicity in rats

BACKGROUND AND PURPOSE: Ifosfamide nephrotoxicity is a serious adverse effect for children undergoing cancer chemotherapy. Our recent in vitro studies have shown that the antioxidant N-acetylcysteine (NAC), which is used extensively as an antidote for paracetamol (acetaminophen) poisoning in childre...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, N, Aleksa, K, Woodland, C, Rieder, M, Koren, G
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2008
Schlagworte:
Research Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2437918/
https://ncbi.nlm.nih.gov/pubmed/18278066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.15
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