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Nephrotoxicity of Polymyxins: Is There Any Difference between Colistimethate and Polymyxin B?

Nephrotoxicity is a common adverse effect of the clinically used polymyxins, colistin and polymyxin B. This adverse effect is dose limiting for both polymyxins, as the plasma polymyxin concentrations associated with renal damage overlap those required for antibacterial effect. Since development of a...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Zavascki, Alexandre P., Nation, Roger L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328560/
https://ncbi.nlm.nih.gov/pubmed/27993859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02319-16
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