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Nephrotoxicity of Polymyxins: Is There Any Difference between Colistimethate and Polymyxin B?

Nephrotoxicity is a common adverse effect of the clinically used polymyxins, colistin and polymyxin B. This adverse effect is dose limiting for both polymyxins, as the plasma polymyxin concentrations associated with renal damage overlap those required for antibacterial effect. Since development of a...

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Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphovsmän: Zavascki, Alexandre P., Nation, Roger L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328560/
https://ncbi.nlm.nih.gov/pubmed/27993859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02319-16
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