Blood–brain barrier opening in Alzheimer’s disease using MR-guided focused ultrasound

Magnetic resonance-guided focused ultrasound in combination with intravenously injected microbubbles has been shown to transiently open the blood–brain barrier, and reduce beta-amyloid and tau pathology in animal models of Alzheimer’s disease. Here, we used focused ultrasound to open the blood–brain...

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Udgivet i:Nat Commun
Main Authors: Lipsman, Nir, Meng, Ying, Bethune, Allison J., Huang, Yuexi, Lam, Benjamin, Masellis, Mario, Herrmann, Nathan, Heyn, Chinthaka, Aubert, Isabelle, Boutet, Alexandre, Smith, Gwenn S., Hynynen, Kullervo, Black, Sandra E.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060168/
https://ncbi.nlm.nih.gov/pubmed/30046032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04529-6
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