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Phenotypic screening identifies a new oxazolone inhibitor of necroptosis and neuroinflammation

Necroptosis is a regulated form of necrosis, which may be critical in the pathogenesis of neurodegenerative diseases. Neuroinflammation, characterized by the activation of glial cells such as microglia, is closely linked with neurodegenerative pathways and constitutes a major mechanism of neural dam...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Death Discov
Päätekijät: Oliveira, Sara R., Dionísio, Pedro A., Brito, Hugo, Franco, Lídia, Rodrigues, Catarina A. B., Guedes, Rita C., Afonso, Carlos A. M., Amaral, Joana D., Rodrigues, Cecília M. P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060125/
https://ncbi.nlm.nih.gov/pubmed/30062059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-018-0067-0
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