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Phenotypic screening identifies a new oxazolone inhibitor of necroptosis and neuroinflammation

Necroptosis is a regulated form of necrosis, which may be critical in the pathogenesis of neurodegenerative diseases. Neuroinflammation, characterized by the activation of glial cells such as microglia, is closely linked with neurodegenerative pathways and constitutes a major mechanism of neural dam...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Oliveira, Sara R., Dionísio, Pedro A., Brito, Hugo, Franco, Lídia, Rodrigues, Catarina A. B., Guedes, Rita C., Afonso, Carlos A. M., Amaral, Joana D., Rodrigues, Cecília M. P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060125/
https://ncbi.nlm.nih.gov/pubmed/30062059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-018-0067-0
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