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Phenotypic screening identifies a new oxazolone inhibitor of necroptosis and neuroinflammation
Necroptosis is a regulated form of necrosis, which may be critical in the pathogenesis of neurodegenerative diseases. Neuroinflammation, characterized by the activation of glial cells such as microglia, is closely linked with neurodegenerative pathways and constitutes a major mechanism of neural dam...
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| Pubblicato in: | Cell Death Discov |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6060125/ https://ncbi.nlm.nih.gov/pubmed/30062059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-018-0067-0 |
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