Intradermal immunization by Ebola virus GP subunit vaccines using microneedle patches protects mice against lethal EBOV challenge

Development of a safe and efficacious filovirus vaccine is of high importance to public health. In this study, we compared immune responses induced by Ebola virus (EBOV) glycoprotein (GP) subunit vaccines via intradermal immunization with microneedle (MN) patches and the conventional intramuscular (...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Liu, Ying, Ye, Ling, Lin, Fang, Gomaa, Yasmine, Flyer, David, Carrion, Ricardo, Patterson, Jean L., Prausnitz, Mark R., Smith, Gale, Glenn, Gregory, Wu, Hua, Compans, Richard W., Yang, Chinglai
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060117/
https://ncbi.nlm.nih.gov/pubmed/30046140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29135-w
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