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A biallelic 36-bp insertion in PIBF1 is associated with Joubert syndrome

Biallelic pathogenic variants in PIBF1 have been identified as one of the genetic etiologies of Joubert syndrome. We report a two-years-old girl with global developmental delay, facial dysmorphism, hypotonia, enlarged cystic kidneys, molar tooth sign and thinning of corpus callosum. A novel homozygo...

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Podrobná bibliografie
Vydáno v:J Hum Genet
Hlavní autoři: Hebbar, Malavika, Kanthi, Anil, Shukla, Anju, Bielas, Stephanie, Girisha, Katta M
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060014/
https://ncbi.nlm.nih.gov/pubmed/29695797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s10038-018-0462-7
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