Increased Afterload Augments Sunitinib-Induced Cardiotoxicity in an Engineered Cardiac Microtissue Model

Sunitinib, a multitargeted oral tyrosine kinase inhibitor, used widely to treat solid tumors, results in hypertension in up to 47% and left ventricular dysfunction in up to 19% of treated individuals. The relative contribution of afterload toward inducing cardiac dysfunction with sunitinib treatment...

Fuld beskrivelse

Na minha lista:

Bibliografiske detaljer
Udgivet i:	JACC Basic Transl Sci
Main Authors:	Truitt, Rachel, Mu, Anbin, Corbin, Elise A., Vite, Alexia, Brandimarto, Jeffrey, Ky, Bonnie, Margulies, Kenneth B.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2018
Fag:	PRECLINICAL RESEARCH
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6059907/ https://ncbi.nlm.nih.gov/pubmed/30062212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2017.12.007
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!

Increased Afterload Augments Sunitinib-Induced Cardiotoxicity in an Engineered Cardiac Microtissue Model

Lignende værker