3299 Dynamic Afterload Cardiac Microtissue Model To Examine Molecular Pathways of Heart Failure

OBJECTIVES/SPECIFIC AIMS: This project aims to determine the key molecular pathways that link increased myocardial wall stress to cardiomyocyte hypertrophy and subsequent heart failure. We will use a cardiac microtissue (CMT) model with dynamically tunable cantilever stiffness to examine changes in...

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Bibliografiset tiedot
Julkaisussa:J Clin Transl Sci
Päätekijät: Ramachandran, Abhinay, Livingston, Carissa, Corbin, Elise, Vite, Alexia, Bennett, Alex, Margulies, Kenneth
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cambridge University Press 2019
Aiheet:
Basic/Translational Science/Team Science
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6799322/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2019.25
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