Eph A10-modified pH-sensitive liposomes loaded with novel triphenylphosphine–docetaxel conjugate possess hierarchical targetability and sufficient antitumor effect both in vitro and in vivo

Mitochondrial-targeting therapy was considered to be a promising approach for the efficient treatment of cancer while positive charge induced nonspecific cytotoxicity severely limits its application. To overcome this drawback, a novel mitochondria targeted conjugate triphenylphosphine-docetaxel (TD)...

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Detalhes bibliográficos
Publicado no:Drug Deliv
Main Authors: Zhang, Jiulong, Yang, Chunrong, Pan, Shuang, Shi, Menghao, Li, Jie, Hu, Haiyang, Qiao, Mingxi, Chen, Dawei, Zhao, Xiuli
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058733/
https://ncbi.nlm.nih.gov/pubmed/29513049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1446475
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