Penetration enhancer-containing spanlastics (PECSs) for transdermal delivery of haloperidol: in vitro characterization, ex vivo permeation and in vivo biodistribution studies

Haloperidol (Hal) is one of the widely used antipsychotic drugs. When orally administered, it suffers from low bioavailability due to hepatic first pass metabolism. This study aimed at developing Hal-loaded penetration enhancer-containing spanlastics (PECSs) to increase transdermal permeation of Hal...

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Detalhes bibliográficos
Publicado no:Drug Deliv
Main Authors: Fahmy, Abdurrahman M., El-Setouhy, Doaa Ahmed, Ibrahim, Ahmed B., Habib, Basant A., Tayel, Saadia A., Bayoumi, Noha A.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058714/
https://ncbi.nlm.nih.gov/pubmed/29219628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2017.1410262
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