Penetration enhancer-containing spanlastics (PECSs) for transdermal delivery of haloperidol: in vitro characterization, ex vivo permeation and in vivo biodistribution studies

Haloperidol (Hal) is one of the widely used antipsychotic drugs. When orally administered, it suffers from low bioavailability due to hepatic first pass metabolism. This study aimed at developing Hal-loaded penetration enhancer-containing spanlastics (PECSs) to increase transdermal permeation of Hal...

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Detalles Bibliográficos
Publicado en:Drug Deliv
Main Authors: Fahmy, Abdurrahman M., El-Setouhy, Doaa Ahmed, Ibrahim, Ahmed B., Habib, Basant A., Tayel, Saadia A., Bayoumi, Noha A.
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2017
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058714/
https://ncbi.nlm.nih.gov/pubmed/29219628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2017.1410262
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