Penetration enhancer-containing spanlastics (PECSs) for transdermal delivery of haloperidol: in vitro characterization, ex vivo permeation and in vivo biodistribution studies

Haloperidol (Hal) is one of the widely used antipsychotic drugs. When orally administered, it suffers from low bioavailability due to hepatic first pass metabolism. This study aimed at developing Hal-loaded penetration enhancer-containing spanlastics (PECSs) to increase transdermal permeation of Hal...

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Dettagli Bibliografici
Pubblicato in:Drug Deliv
Autori principali: Fahmy, Abdurrahman M., El-Setouhy, Doaa Ahmed, Ibrahim, Ahmed B., Habib, Basant A., Tayel, Saadia A., Bayoumi, Noha A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058714/
https://ncbi.nlm.nih.gov/pubmed/29219628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2017.1410262
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