Statistical optimization of hyaluronic acid enriched ultradeformable elastosomes for ocular delivery of voriconazole via Box-Behnken design: in vitro characterization and in vivo evaluation

Voriconazole (VCZ) is a well-known broad spectrum triazole antifungal, mainly used orally and intravenously. The study aimed to formulate VCZ into ultradeformable elastosomes for the topical treatment of ocular fungal keratitis. Different formulae were prepared using a modified ethanol injection met...

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Detalles Bibliográficos
Publicado en:Drug Deliv
Main Authors: Fahmy, Abdurrahman Muhammad, Hassan, Mariam, El-Setouhy, Doaa Ahmed, Tayel, Saadia Ahmed, Al-Mahallawi, Abdulaziz Mohsen
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2020
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875553/
https://ncbi.nlm.nih.gov/pubmed/33342315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2020.1858997
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