Regression of prostate tumors after intravenous administration of lactoferrin-bearing polypropylenimine dendriplexes encoding TNF-α, TRAIL, and interleukin-12

The possibility of using gene therapy for the treatment of prostate cancer is limited by the lack of intravenously administered delivery systems able to safely and selectively deliver therapeutic genes to tumors. Given that lactoferrin (Lf) receptors are overexpressed on prostate cancer cells, we hy...

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Detalhes bibliográficos
Publicado no:Drug Deliv
Main Authors: Altwaijry, Najla, Somani, Sukrut, Parkinson, John A., Tate, Rothwelle J., Keating, Patricia, Warzecha, Monika, Mackenzie, Graeme R., Leung, Hing Y., Dufès, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058574/
https://ncbi.nlm.nih.gov/pubmed/29493296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1440666
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