Regression of prostate tumors after intravenous administration of lactoferrin-bearing polypropylenimine dendriplexes encoding TNF-α, TRAIL, and interleukin-12

The possibility of using gene therapy for the treatment of prostate cancer is limited by the lack of intravenously administered delivery systems able to safely and selectively deliver therapeutic genes to tumors. Given that lactoferrin (Lf) receptors are overexpressed on prostate cancer cells, we hy...

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Bibliografische gegevens
Gepubliceerd in:Drug Deliv
Hoofdauteurs: Altwaijry, Najla, Somani, Sukrut, Parkinson, John A., Tate, Rothwelle J., Keating, Patricia, Warzecha, Monika, Mackenzie, Graeme R., Leung, Hing Y., Dufès, Christine
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058574/
https://ncbi.nlm.nih.gov/pubmed/29493296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1440666
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