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Enhancing coevolution-based contact prediction by imposing structural self-consistency of the contacts

Based on the development of new algorithms and growth of sequence databases, it has recently become possible to build robust higher-order sequence models based on sets of aligned protein sequences. Such models have proven useful in de novo structure prediction, where the sequence models are used to...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kassem, Maher M., Christoffersen, Lars B., Cavalli, Andrea, Lindorff-Larsen, Kresten
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057941/
https://ncbi.nlm.nih.gov/pubmed/30042380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29357-y
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