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Integrated Platform for Monitoring Single-cell MAPK Kinetics in Computer-controlled Temporal Stimulations

Extracellular response kinase (ERK) is one of the key regulator of cell fate, such as proliferation, differentiation and cell migration. Here, we propose a novel experimental pipeline to learn ERK kinetics by temporal growth factor (GF) stimulation. High signal-to-noise ratio of genetically encoded...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ryu, Hyunryul, Chung, Minhwan, Song, Jiyoung, Lee, Sung Sik, Pertz, Olivier, Jeon, Noo Li
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057930/
https://ncbi.nlm.nih.gov/pubmed/30042437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28873-1
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