Frequency modulation of ERK activation dynamics rewires cell fate

Transient versus sustained ERK MAP kinase (MAPK) activation dynamics induce proliferation versus differentiation in response to epidermal (EGF) or nerve (NGF) growth factors in PC‐12 cells. Duration of ERK activation has therefore been proposed to specify cell fate decisions. Using a biosensor to me...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Syst Biol
मुख्य लेखकों: Ryu, Hyunryul, Chung, Minhwan, Dobrzyński, Maciej, Fey, Dirk, Blum, Yannick, Lee, Sung Sik, Peter, Matthias, Kholodenko, Boris N, Jeon, Noo Li, Pertz, Olivier
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley and Sons Inc. 2015
विषय:
Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670727/
https://ncbi.nlm.nih.gov/pubmed/26613961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20156458
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