Boosting phagocytosis and anti‐inflammatory phenotype in microglia mediates neuroprotection by PPARγ agonist MDG548 in Parkinson's disease models

BACKGROUND AND PURPOSE: Microglial phenotype and phagocytic activity are deregulated in Parkinson's disease (PD). PPARγ agonists are neuroprotective in experimental PD, but their role in regulating microglial phenotype and phagocytosis has been poorly investigated. We addressed it by using the...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Br J Pharmacol
Main Authors: Lecca, Daniela, Janda, Elzbieta, Mulas, Giovanna, Diana, Andrea, Martino, Concetta, Angius, Fabrizio, Spolitu, Stefano, Casu, Maria Antonietta, Simbula, Gabriella, Boi, Laura, Batetta, Barbara, Spiga, Saturnino, Carta, Anna R
פורמט: Artigo
שפה:Inglês
יצא לאור: John Wiley and Sons Inc. 2018
נושאים:
Research Papers
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057897/
https://ncbi.nlm.nih.gov/pubmed/29570770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14214
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים