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Multisite dependency of an E3 ligase controls monoubiquitylation-dependent cell fate decisions

Metazoan development depends on tightly regulated gene expression programs that instruct progenitor cells to adopt specialized fates. Recent work found that posttranslational modifications, such as monoubiquitylation, can determine cell fate also independently of effects on transcription, yet how mo...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Werner, Achim, Baur, Regina, Teerikorpi, Nia, Kaya, Deniz U, Rape, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057744/
https://ncbi.nlm.nih.gov/pubmed/29999490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.35407
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