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Multisite dependency of an E3 ligase controls monoubiquitylation-dependent cell fate decisions

Metazoan development depends on tightly regulated gene expression programs that instruct progenitor cells to adopt specialized fates. Recent work found that posttranslational modifications, such as monoubiquitylation, can determine cell fate also independently of effects on transcription, yet how mo...

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Bibliographische Detailangaben
Veröffentlicht in:eLife
Hauptverfasser: Werner, Achim, Baur, Regina, Teerikorpi, Nia, Kaya, Deniz U, Rape, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057744/
https://ncbi.nlm.nih.gov/pubmed/29999490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.35407
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