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Tenascin-X, Congenital Adrenal Hyperplasia, and the CAH-X Syndrome

Mutations of the CYP21A2 gene encoding adrenal 21-hydroxylase cause congenital adrenal hyperplasia (CAH). The CYP21A2 gene is partially overlapped by the TNXB gene, which encodes an extracellular matrix protein called Tenascin-X (TNX). Mutations affecting both alleles of TNXB cause a severe, autosom...

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Bibliografiske detaljer
Udgivet i:Horm Res Paediatr
Main Authors: Miller, Walter L, Merke, Deborah P
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057477/
https://ncbi.nlm.nih.gov/pubmed/29734195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000481911
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