APEX1 Polymorphism and Mercaptopurine-Related Early Onset Neutropenia in Pediatric Acute Lymphoblastic Leukemia

PURPOSE: Mercaptopurine (MP) is one of the main chemotherapeutics for acute lymphoblastic leukemia (ALL). To improve treatment outcomes, constant MP dose titration is essential to maintain steady drug exposure, while minimizing myelosuppression. We performed two-stage analyses to identify genetic de...

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Detalhes bibliográficos
Publicado no:Cancer Res Treat
Main Authors: Kim, Hyery, Seo, Heewon, Park, Yoomi, Min, Byung-Joo, Seo, Myung-Eui, Park, Kyung Duk, Shin, Hee Young, Kim, Ju Han, Kang, Hyoung Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Cancer Association 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056975/
https://ncbi.nlm.nih.gov/pubmed/28882023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2017.351
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