APEX1 Polymorphism and Mercaptopurine-Related Early Onset Neutropenia in Pediatric Acute Lymphoblastic Leukemia

PURPOSE: Mercaptopurine (MP) is one of the main chemotherapeutics for acute lymphoblastic leukemia (ALL). To improve treatment outcomes, constant MP dose titration is essential to maintain steady drug exposure, while minimizing myelosuppression. We performed two-stage analyses to identify genetic de...

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Dettagli Bibliografici
Pubblicato in:Cancer Res Treat
Autori principali: Kim, Hyery, Seo, Heewon, Park, Yoomi, Min, Byung-Joo, Seo, Myung-Eui, Park, Kyung Duk, Shin, Hee Young, Kim, Ju Han, Kang, Hyoung Jin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Cancer Association 2018
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056975/
https://ncbi.nlm.nih.gov/pubmed/28882023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2017.351
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