Reversal of loss of bone mass in old mice treated with mefloquine

Aging is accompanied by imbalanced bone remodeling, elevated osteocyte apoptosis, and decreased bone mass and mechanical properties; and improved pharmacologic approaches to counteract bone deterioration with aging are needed. We examined herein the effect of mefloquine, a drug used to treat malaria...

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Bibliographic Details
Published in:Bone
Main Authors: Pacheco-Costa, Rafael, Davis, Hannah M., Atkinson, Emily G., Dilley, Julian E., Byiringiro, Innocent, Aref, Mohammad W., Allen, Matthew R., Bellido, Teresita, Plotkin, Lilian I.
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056320/
https://ncbi.nlm.nih.gov/pubmed/29879544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2018.06.002
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