Tariquidar Sensitizes Multiple Myeloma Cells to Proteasome Inhibitors via Reduction of Hypoxia-Induced P-gp-Mediated Drug Resistance

Multiple myeloma (MM) presents a poor prognosis and high lethality of patients due to development of drug resistance. P-glycoprotein (P-gp), a drug-efflux transporter, is upregulated in MM patients post-chemotherapy and is involved in the development of drug resistance since many anti-myeloma drugs...

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Detalhes bibliográficos
Publicado no:Leuk Lymphoma
Main Authors: Muz, Barbara, Kusdono, Hubert D, Azab, Feda, de la Puente, Pilar, Federico, Cinzia, Fiala, Mark, Vij, Ravi, Salama, Noha N, Azab, Abdel Kareem
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056270/
https://ncbi.nlm.nih.gov/pubmed/28509582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2017.1319052
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