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The role of hypoxia in cancer progression, angiogenesis, metastasis, and resistance to therapy
Hypoxia is a non-physiological level of oxygen tension, a phenomenon common in a majority of malignant tumors. Tumor-hypoxia leads to advanced but dysfunctional vascularization and acquisition of epithelial-to-mesenchymal transition phenotype resulting in cell mobility and metastasis. Hypoxia alters...
Gardado en:
| Publicado en: | Hypoxia (Auckl) |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Dove Medical Press
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5045092/ https://ncbi.nlm.nih.gov/pubmed/27774485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/HP.S93413 |
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