Reactivation of endogenous retroviral elements via treatment with DNMT- and HDAC-inhibitors

Inhibitors of DNA methyltransferases (DNMTis) or histone deacetylases (HDACis) are epigenetic drugs which are investigated since decades. Several have been approved and are applied in the treatment of hematopoietic and lymphatic malignancies, although their mode of action has not been fully understo...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Daskalakis, Michael, Brocks, David, Sheng, Yi-Hua, Islam, Md Saiful, Ressnerova, Alzbeta, Assenov, Yassen, Milde, Till, Oehme, Ina, Witt, Olaf, Goyal, Ashish, Kühn, Alexander, Hartmann, Mark, Weichenhan, Dieter, Jung, Manfred, Plass, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056222/
https://ncbi.nlm.nih.gov/pubmed/29633898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1442623
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