Human MAIT cells show metabolic quiescence with rapid glucose‐dependent upregulation of granzyme B upon stimulation

Mucosal‐associated invariant T (MAIT) cells are a well‐characterized innate‐like T cell population abundant in the human liver, peripheral tissues and blood. MAIT cells serve in the first line of defense against infections, through engagement of their T cell receptor, which recognizes microbial meta...

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Detalhes bibliográficos
Publicado no:Immunol Cell Biol
Main Authors: Zinser, Madeleine E, Highton, Andrew J, Kurioka, Ayako, Kronsteiner, Barbara, Hagel, Joachim, Leng, Tianqi, Marchi, Emanuele, Phetsouphanh, Chansavath, Willberg, Chris B, Dunachie, Susanna J, Klenerman, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6055666/
https://ncbi.nlm.nih.gov/pubmed/29423939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imcb.12020
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