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Distinct ways of G:U recognition by conserved tRNA binding motifs

Throughout three domains of life, alanyl-tRNA synthetases (AlaRSs) recognize a G3:U70 base pair in the acceptor stem of tRNA(Ala) as the major identity determinant of tRNA(Ala). The crystal structure of the archaeon Archaeoglobus fulgidus AlaRS in complex with tRNA(Ala) provided the basis for G3:U70...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Chong, Yeeting E., Guo, Min, Yang, Xiang-Lei, Kuhle, Bernhard, Naganuma, Masahiro, Sekine, Shun-ichi, Yokoyama, Shigeyuki, Schimmel, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6055181/
https://ncbi.nlm.nih.gov/pubmed/29967150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807109115
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