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Unique protein architecture of alanyl-tRNA synthetase for aminoacylation, editing, and dimerization

Alanyl-tRNA synthetase (AlaRS) specifically recognizes the major identity determinant, the G3:U70 base pair, in the acceptor stem of tRNA(Ala) by both the tRNA-recognition and editing domains. In this study, we solved the crystal structures of 2 halves of Archaeoglobus fulgidus AlaRS: AlaRS-ΔC, comp...

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Autori principali: Naganuma, Masahiro, Sekine, Shun-ichi, Fukunaga, Ryuya, Yokoyama, Shigeyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689022/
https://ncbi.nlm.nih.gov/pubmed/19423669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901572106
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