Ablation of PM20D1 reveals N-acyl amino acid control of metabolism and nociception

N-acyl amino acids (NAAs) are a structurally diverse class of bioactive signaling lipids whose endogenous functions have largely remained uncharacterized. To clarify the physiologic roles of NAAs, we generated mice deficient in the circulating enzyme peptidase M20 domain-containing 1 (PM20D1). Globa...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Long, Jonathan Z., Roche, Alexander M., Berdan, Charles A., Louie, Sharon M., Roberts, Amanda J., Svensson, Katrin J., Dou, Florence Y., Bateman, Leslie A., Mina, Amir I., Deng, Zhaoming, Jedrychowski, Mark P., Lin, Hua, Kamenecka, Theodore M., Asara, John M., Griffin, Patrick R., Banks, Alexander S., Nomura, Daniel K., Spiegelman, Bruce M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6055169/
https://ncbi.nlm.nih.gov/pubmed/29967167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1803389115
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