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Hypoxia-Driven Immunosuppressive Metabolites in the Tumor Microenvironment: New Approaches for Combinational Immunotherapy

Hypoxia is not only a prominent contributor to the heterogeneity of solid tumors but also a crucial stressor in the microenvironment to drive adaptations for tumors to evade immunosurveillance. Herein, we discuss the potential role of hypoxia within the microenvironment contributing to immune resist...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Li, Yiliang, Patel, Sapna Pradyuman, Roszik, Jason, Qin, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054965/
https://ncbi.nlm.nih.gov/pubmed/30061885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01591
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