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A Utility-Based Design for Randomized Comparative Trials with Ordinal Outcomes and Prognostic Subgroups
A design is proposed for randomized comparative trials with ordinal outcomes and prognostic subgroups. The design accounts for patient heterogeneity by allowing possibly different comparative conclusions within subgroups. The comparative testing criterion is based on utilities for the levels of the...
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| Veröffentlicht in: | Biometrics |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6054910/ https://ncbi.nlm.nih.gov/pubmed/29359314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.12842 |
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