Candidate biomarkers for the diagnosis and prognosis of drug-induced liver injury: an international collaborative effort

Current blood biomarkers are suboptimal in detecting drug-induced liver injury (DILI) and predicting its outcome. We sought to characterize the natural variabilty and performance characteristics of fourteen promising DILI biomarker candidates. Serum or plasma from multiple cohorts of healthy volunte...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Church, Rachel J., Kullak-Ublick, Gerd A., Aubrecht, Jiri, Bonkovsky, Herbert L., Chalasani, Naga, Fontana, Robert J., Goepfert, Jens C., Hackman, Frances, King, Nicholas M. P., Kirby, Simon, Kirby, Patrick, Marcinak, John, Ormarsdottir, Sif, Schomaker, Shelli J., Schuppe-Koistinen, Ina, Wolenski, Francis, Arber, Nadir, Merz, Michael, Sauer, John-Michael, Andrade, Raul J., van Bömmel, Florian, Poynard, Thierry, Watkins, Paul B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054900/
https://ncbi.nlm.nih.gov/pubmed/29357190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29802
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