Candidate biomarkers for the diagnosis and prognosis of drug-induced liver injury: an international collaborative effort

Current blood biomarkers are suboptimal in detecting drug-induced liver injury (DILI) and predicting its outcome. We sought to characterize the natural variabilty and performance characteristics of fourteen promising DILI biomarker candidates. Serum or plasma from multiple cohorts of healthy volunte...

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Vydáno v:Hepatology
Hlavní autoři: Church, Rachel J., Kullak-Ublick, Gerd A., Aubrecht, Jiri, Bonkovsky, Herbert L., Chalasani, Naga, Fontana, Robert J., Goepfert, Jens C., Hackman, Frances, King, Nicholas M. P., Kirby, Simon, Kirby, Patrick, Marcinak, John, Ormarsdottir, Sif, Schomaker, Shelli J., Schuppe-Koistinen, Ina, Wolenski, Francis, Arber, Nadir, Merz, Michael, Sauer, John-Michael, Andrade, Raul J., van Bömmel, Florian, Poynard, Thierry, Watkins, Paul B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054900/
https://ncbi.nlm.nih.gov/pubmed/29357190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29802
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