Candidate biomarkers for the diagnosis and prognosis of drug-induced liver injury: an international collaborative effort

Current blood biomarkers are suboptimal in detecting drug-induced liver injury (DILI) and predicting its outcome. We sought to characterize the natural variabilty and performance characteristics of fourteen promising DILI biomarker candidates. Serum or plasma from multiple cohorts of healthy volunte...

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Udgivet i:Hepatology
Main Authors: Church, Rachel J., Kullak-Ublick, Gerd A., Aubrecht, Jiri, Bonkovsky, Herbert L., Chalasani, Naga, Fontana, Robert J., Goepfert, Jens C., Hackman, Frances, King, Nicholas M. P., Kirby, Simon, Kirby, Patrick, Marcinak, John, Ormarsdottir, Sif, Schomaker, Shelli J., Schuppe-Koistinen, Ina, Wolenski, Francis, Arber, Nadir, Merz, Michael, Sauer, John-Michael, Andrade, Raul J., van Bömmel, Florian, Poynard, Thierry, Watkins, Paul B.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054900/
https://ncbi.nlm.nih.gov/pubmed/29357190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29802
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