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Emerging hepatotoxicity biomarkers and their potential to improve understanding and management of drug-induced liver injury

Biomarkers of drug-induced liver injury (DILI) are essential for the diagnosis of severe cases of DILI in clinical trials and clinical practice, but the currently used biomarker paradigm detects damage after it has occurred and has limited prognostic value. The development of new biomarker strategie...

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Autors principals: Aubrecht, Jiri, Schomaker, Shelli J, Amacher, David E
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979132/
https://ncbi.nlm.nih.gov/pubmed/24073687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm489
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