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Novel pharmacological maps of protein lysine methyltransferases: key for target deorphanization

Epigenetic therapies are being investigated for the treatment of cancer, cognitive disorders, metabolic alterations and autoinmune diseases. Among the different epigenetic target families, protein lysine methyltransferases (PKMTs), are especially interesting because it is believed that their inhibit...

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Detalhes bibliográficos
Publicado no:J Cheminform
Main Authors: Rabal, Obdulia, Castellar, Andrea, Oyarzabal, Julen
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054832/
https://ncbi.nlm.nih.gov/pubmed/30032331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13321-018-0288-5
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