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Novel pharmacological maps of protein lysine methyltransferases: key for target deorphanization

Epigenetic therapies are being investigated for the treatment of cancer, cognitive disorders, metabolic alterations and autoinmune diseases. Among the different epigenetic target families, protein lysine methyltransferases (PKMTs), are especially interesting because it is believed that their inhibit...

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Dettagli Bibliografici
Pubblicato in:J Cheminform
Autori principali: Rabal, Obdulia, Castellar, Andrea, Oyarzabal, Julen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054832/
https://ncbi.nlm.nih.gov/pubmed/30032331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13321-018-0288-5
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