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Novel pharmacological maps of protein lysine methyltransferases: key for target deorphanization

Epigenetic therapies are being investigated for the treatment of cancer, cognitive disorders, metabolic alterations and autoinmune diseases. Among the different epigenetic target families, protein lysine methyltransferases (PKMTs), are especially interesting because it is believed that their inhibit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cheminform
Hauptverfasser: Rabal, Obdulia, Castellar, Andrea, Oyarzabal, Julen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054832/
https://ncbi.nlm.nih.gov/pubmed/30032331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13321-018-0288-5
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