TIGIT(+) iTregs elicited by human regulatory macrophages control T cell immunity

Human regulatory macrophages (Mreg) have shown early clinical promise as a cell-based adjunct immunosuppressive therapy in solid organ transplantation. It is hypothesised that recipient CD4(+) T cell responses are actively regulated through direct allorecognition of donor-derived Mregs. Here we show...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Riquelme, Paloma, Haarer, Jan, Kammler, Anja, Walter, Lisa, Tomiuk, Stefan, Ahrens, Norbert, Wege, Anja K., Goecze, Ivan, Zecher, Daniel, Banas, Bernhard, Spang, Rainer, Fändrich, Fred, Lutz, Manfred B., Sawitzki, Birgit, Schlitt, Hans J., Ochando, Jordi, Geissler, Edward K., Hutchinson, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054648/
https://ncbi.nlm.nih.gov/pubmed/30030423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05167-8
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