In question: the scientific value of preclinical safety pharmacology and toxicology studies with cell-based therapies

A new cell-based medicinal product containing human regulatory macrophages, known as Mreg_UKR, has been developed and conforms to expectations of a therapeutic drug. Here, Mreg_UKR was subjected to pharmacokinetic, safety pharmacology, and toxicological testing, which identified no adverse reactions...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Broichhausen, Christiane, Riquelme, Paloma, Ahrens, Norbert, Wege, Anja K, Koehl, Gudrun E, Schlitt, Hans J, Banas, Bernhard, Fändrich, Fred, Geissler, Edward K, Hutchinson, James A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362366/
https://ncbi.nlm.nih.gov/pubmed/26015968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2014.26
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