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Targeting ALK in pediatric RMS does not induce antitumor activity in vivo

PURPOSE: The anaplastic lymphoma kinase (ALK) has been demonstrated to be a valid clinical target in diseases such as anaplastic large cell lymphoma and non-small cell lung cancer. Recent studies have indicated that ALK is overexpressed in pediatric rhabdomyosarcoma (RMS) and hence we hypothesized t...

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Vydáno v:Cancer Chemother Pharmacol
Hlavní autoři: Wierdl, Monika, Tsurkan, Lyudmila, Chi, Liying, Hatfield, M. Jason, Tollemar, Viktor, Bradley, Cori, Chen, Xiang, Qu, Chunxu, Potter, Philip M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054567/
https://ncbi.nlm.nih.gov/pubmed/29855693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-018-3615-7
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