Hydroxyproline Metabolism and Oxalate Synthesis in Primary Hyperoxaluria

Background Endogenous oxalate synthesis contributes to calcium oxalate stone disease and is markedly increased in the inherited primary hyperoxaluria (PH) disorders. The incomplete knowledge regarding oxalate synthesis complicates discovery of new treatments. Hydroxyproline (Hyp) metabolism results...

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Bibliographic Details
Published in:J Am Soc Nephrol
Main Authors: Fargue, Sonia, Milliner, Dawn S., Knight, John, Olson, Julie B., Lowther, W. Todd, Holmes, Ross P.
Format: Artigo
Language:Inglês
Published: American Society of Nephrology 2018
Subjects:
Basic Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054332/
https://ncbi.nlm.nih.gov/pubmed/29588429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017040390
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