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The Effects of the Inactivation of Hydroxyproline Dehydrogenase on Urinary Oxalate and Glycolate Excretion in Mouse Models of Primary Hyperoxaluria
The major clinical manifestation of the Primary Hyperoxalurias (PH) is increased production of oxalate, as a consequence of genetic mutations that lead to aberrant glyoxylate and hydroxyproline metabolism. Hyperoxaluria can lead to the formation of calcium-oxalate kidney stones, nephrocalcinosis and...
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| Publicado no: | Biochim Biophys Acta Mol Basis Dis |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7047938/ https://ncbi.nlm.nih.gov/pubmed/31821850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2019.165633 |
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