Effects of sofosbuvir-based hepatitis C treatment on the pharmacokinetics of tenofovir in HIV/HCV-coinfected individuals receiving tenofovir disoproxil fumarate

BACKGROUND: The nucleotide analogues tenofovir and sofosbuvir are considered to have low potential for drug interactions. OBJECTIVES: To determine the effect of sofosbuvir-based HCV treatment on plasma concentrations of tenofovir and cellular concentrations of tenofovir diphosphate. METHODS: HIV-inf...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: MacBrayne, Christine E, Marks, Kristen M, Fierer, Daniel S, Naggie, Susanna, Chung, Raymond T, Hughes, Michael D, Kim, Arthur Y, Peters, Marion G, Brainard, Diana M, Seifert, Sharon M, Castillo-Mancilla, Jose R, Bushman, Lane R, Anderson, Peter L, Kiser, Jennifer J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054189/
https://ncbi.nlm.nih.gov/pubmed/29746648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dky146
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