A carregar...
De novo design of isopeptide bond-tethered triple-stranded coiled coils with exceptional resistance to unfolding and proteolysis: implication for developing antiviral therapeutics
Isopeptide bond-tethered triple-stranded coiled coils of HIV-1 gp41 N-terminal heptad repeat (NHR) peptides have been designed with de novo auxiliaries to guide site-directed trimerized cross-linking. The presence of isopeptide bridges in the rationally designed trimerization motifs provides extraor...
Na minha lista:
| Publicado no: | Chem Sci |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2015
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6054081/ https://ncbi.nlm.nih.gov/pubmed/30090269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc02220g |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|