Modeling APC mutagenesis and familial adenomatous polyposis using human iPS cells

Mutations in the gene Adenomatous Polyposis Coli or APC appear in most sporadic cases of colorectal cancer and it is the most frequent mutation causing hereditary Familial Adenomatous Polyposis. The detailed molecular mechanism by which APC mutations predispose to the development of colorectal cance...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Sommer, Cesar A., Capilla, Amalia, Molina-Estevez, Francisco J., Gianotti-Sommer, Andreia, Skvir, Nicholas, Caballero, Ignacio, Chowdhury, Sanjib, Mostoslavsky, Gustavo
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2018
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053155/
https://ncbi.nlm.nih.gov/pubmed/30024920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200657
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