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Modeling APC mutagenesis and familial adenomatous polyposis using human iPS cells
Mutations in the gene Adenomatous Polyposis Coli or APC appear in most sporadic cases of colorectal cancer and it is the most frequent mutation causing hereditary Familial Adenomatous Polyposis. The detailed molecular mechanism by which APC mutations predispose to the development of colorectal cance...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6053155/ https://ncbi.nlm.nih.gov/pubmed/30024920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200657 |
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