Modeling APC mutagenesis and familial adenomatous polyposis using human iPS cells

Mutations in the gene Adenomatous Polyposis Coli or APC appear in most sporadic cases of colorectal cancer and it is the most frequent mutation causing hereditary Familial Adenomatous Polyposis. The detailed molecular mechanism by which APC mutations predispose to the development of colorectal cance...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Sommer, Cesar A., Capilla, Amalia, Molina-Estevez, Francisco J., Gianotti-Sommer, Andreia, Skvir, Nicholas, Caballero, Ignacio, Chowdhury, Sanjib, Mostoslavsky, Gustavo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2018
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053155/
https://ncbi.nlm.nih.gov/pubmed/30024920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200657
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